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具有纳米粒子混合输送载体和它们的吸收途径的细胞透

Moataz Dowaidar¹

¹Bioengineering Department, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran 31261, Saudi Arabia; Interdisciplinary Research Center for Hydrogen Technologies and Carbon Management, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran 31261, Saudi Arabia; Biosystems and Machines Research Center, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran 31261, Saudi Arabia.

|May 26, 2024

概括

细胞透 (CPPs) 增强了治疗分子进入细胞的传递. 本综述涵盖了CPP分类,机制及其与纳米颗粒用于药物输送应用的使用.

科学领域:

生物化学生物化学
分子生物学分子生物学
纳米技术纳米技术

背景情况:

细胞透 (CPPs) 促进分子穿越细胞膜的运输.
在制药和医疗应用中,CPP对于输送有效载荷至关重要.
大多数研究的细胞透剂都是基于的.

研究的目的:

提供细胞透 (CPPs) 的全面概述.
讨论CPP的分类,吸收机制和应用.
探索CPP与纳米颗粒的整合,以提高交付效率.

主要方法:

关于CPP,混合载体和纳米粒子系统的文献综述.
对CPP分类和细胞吸收途径的分析.
对CPP-纳米粒子结合物的治疗潜力的检查.

主要成果:

CPP提供了一个多功能平台,用于运送各种货物,如siRNA和纳米粒子.
将CPP与脂质和聚合物结合的混合载体系统显示出有前途.
将CPP与纳米颗粒结合起来,可以有效地提供有针对性的治疗.

结论:

细胞透是细胞内输送的有价值的工具.
混合CPP-纳米粒子系统具有显著的治疗潜力.
对CPP的临床前和临床应用进行进一步的研究是有必要的.

关键词:

共同保护计划 (CPPs) 是一个共同保护计划.细胞透的.药物输送系统药物输送系统细胞内核的机制细胞内核的机制混合交付向量混合交付向量细胞内吸收量细胞内吸收量纳米粒子-CPP结合剂结合剂纳米颗粒纳米颗粒纳米技术在医学中的应用有针对性的药物输送.治疗性的纳米载体.

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