重复的前置神经电刺激 (VeNS) 降低了中度至重度失眠的严重程度;一个随机的假控制试验;modius睡眠研究
Grace Curry1, Teris Cheung2, Shu-Dong Zhang3
1School of Biomedical Sciences, Ulster University, Cromore Road, Coleraine, BT52 1SA, United Kingdom.
Brain stimulation
|May 26, 2024
概括
使用Modius Sleep设备进行的前置神经电刺激 (VeNS) 与假刺激相比,在四周内显著改善了失眠症状. 这种非侵入性治疗为有效管理慢性失眠提供了一个有希望的新选择.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 生物医学工程 生物医学工程
背景情况:
- 失眠是一种广泛的健康问题,具有显著的不良健康影响.
- 迫切需要新的,有效的,安全的,低成本的长期失眠治疗.
- 电气前置神经刺激 (VeNS) 已经显示出改善失眠的潜力,但假控制试验的强有力的证据有限.
研究的目的:
- 评估通过Modius Sleep设备重复VeNS在改善失眠症状方面的有效性.
- 用失眠严重程度指数 (ISI) 来比较VeNS在4周治疗期间对假刺激的有效性.
主要方法:
- 这是一项双盲,多地点,随机,假控制的双盲研究.
- 147名患有中度至重度失眠症 (ISI≥15) 的参与者被随机分配到接受VeNS或假刺激.
- 参与者每天使用指定的设备30分钟,每周至少5天,持续4周.
主要成果:
- 与虚假组相比,VeNS组在ISI分数 (2.26分,p=0.002) 中的平均降低明显更大.
- 每项协议分析显示,VeNS组的平均ISI得分下降了5.8,超过一半的患者获得了临床显著的改善.
- 与虚假组相比,VeNS组在SF-36生活质量能量/疲劳领域也显示出更好的改善.
结论:
- 使用VeNS的Modius Sleep为失眠治疗提供了一个潜在的非侵入性,安全和临床上有意义的替代方案.
- 这项研究提供了强有力的证据,支持VeNS用于治疗慢性失眠.
- 进一步的研究可能会探索这种技术的长期疗效和更广泛的应用.
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