二极性障碍复发的临床,社会人口和环境预测因素:系统性审查
Anna Giménez-Palomo1, Helena Andreu1, Luis Olivier1
1Bipolar and Depressive Disorders Unit, Hospital Clinic de Barcelona, c. Villarroel, 170, 08036 Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), c. Villarroel, 170, 08036 Barcelona, Spain; Institute of Neurosciences (UBNeuro), Spain.
Journal of affective disorders
|May 26, 2024
概括
确定双相情感障碍 (BD) 复发的危险因素是关键. 家庭病史,早期发病和失业等因素与更糟糕的结果有关,有助于识别高风险患者.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 临床心理学 临床心理学
- 流行病学 流行病学
背景情况:
- 双极性障碍 (BD) 是一种慢性,复发性疾病.
- 确定复发的预后因素对于管理BD至关重要.
- 了解风险因素有助于识别高风险个体.
研究的目的:
- 系统地审查对影响BD复发的社会人口学,临床和环境因素的文献.
- 分析与BD患者的临床复发,复发和住院相关的因素.
主要方法:
- 在PubMed,Cochrane图书馆和科学网络的系统文献搜索.
- 包括58个符合预先定义的标准的文章.
- 根据评估的风险因素类型分组研究.
主要成果:
- 家庭/个人精神病史,严重发作,早期发作,快速循环,低功能和认知问题预测复发.
- 失业,低学历,社会适应不良,生活事件增加了病例的频率.
- 大麻使用与更高的再入院率有关.
结论:
- 几个因素与较差的BD预后有关,使得识别高风险患者.
- 可修改的风险因素提供了潜在的治疗点.
- 需要进一步的研究来澄清特定风险因素的影响.
相关概念视频
Psychological and Sociocultural Causes of Schizophrenia
83
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
83
Bipolar Disorder
67
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
67
Depressive Disorders: Etiology
68
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
68
Biological Causes of Schizophrenia
55
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
55
Mania and Antimanic Drugs: Overview
172
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
172
Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K


