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Updated: Jun 25, 2025

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通过光遗传诱导RIPK3寡合化,空间时间控制炎症性狂热细胞死亡

Teak-Jung Oh1, Vishnu Krishnamurthy2, Jeong Won Han1

  • 1Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Journal of molecular biology
|May 26, 2024
PubMed
概括

研究人员开发了一种新的光遗传工具,即可光激活的受体相互作用蛋白激酶3 (La-RIPK3),用于精确控制细胞亡,这是一个被编程的细胞死亡途径. 该系统允许光学诱导RIPK3的寡合化,从而实现免疫调节的新策略.

关键词:
在RIPK3中使用RIPK3.在RNA-seqqq.临床细胞死亡 临床细胞死亡尸体亡 (necroptosis) 是一种致死症.视觉遗传学 视觉遗传学

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