创伤后应激障碍对心血管的影响:系统性审查和元分析
Bijaya K Padhi1, Mahalaqua Nazli Khatib2, Hashem Abu Serhan3
1Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Current problems in cardiology
|May 26, 2024
概括
创伤后应激障碍 (PTSD) 显著增加了心血管疾病 (CVD) 的风险,包括心脏病发作和中风. 对PTSD患者的综合护理对于管理这些心血管风险的增加至关重要.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 创伤后应激障碍 (PTSD) 与心理健康以外的风险增加有关,特别是心血管疾病 (CVD).
- 新出现的证据突出显示,PTSD与各种心血管结果之间存在明显的关联.
研究的目的:
- 系统地审查和对现有的观察性研究进行元分析.
- 综合关于PTSD和心血管结果之间的关联的证据.
主要方法:
- 进行了全面的文献搜索,直到2024年3月15日.
- 包括评估PTSD和心血管结果的观察性研究.
- 通过I2统计评估异质性的随机效应模型进行的元分析.
主要成果:
- 分析了20项涉及超过3.35万名参与者的研究.
- 创伤后应激障碍与任何心血管疾病 (HR=1.417),心肌梗塞 (MI) (HR=1.415) 和中风 (HR=2.074) 的风险增加有关.
- 对于中风和主要心血管不良事件 (MACE) 观察到显著的异质性和出版偏差.
结论:
- 这一元分析证实PTSD与心血管疾病风险更高有关.
- 将心血管风险管理纳入对PTSD患者的精神病治疗是必不可少的.
- 未来的研究应该探索用于管理PTSD和相关心血管疾病风险的机制和干预措施.
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