Jove
Visualize
联系我们

相关概念视频

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

93
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
93
Aging01:26

Aging

48
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
48
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

465
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
465
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
Dementia01:30

Dementia

111
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
111
Longitudinal Research02:20

Longitudinal Research

12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Independent prognostic value of peak width of skeletonized mean diffusivity on clinical progression in Alzheimer's disease.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Subtypes of brain change in aging and their associations with cognition and Alzheimer's disease biomarkers.

Neurobiology of aging·2024
Same author

Fetal influence on the human brain through the lifespan.

eLife·2024
Same author

Subtypes of brain change in aging and their associations with cognition and Alzheimer's disease biomarkers.

bioRxiv : the preprint server for biology·2024
Same author

Matrix metalloproteinases are associated with brain atrophy in cognitively unimpaired individuals.

Neurobiology of aging·2023
Same author

Associations of neuroinflammatory IL-6 and IL-8 with brain atrophy, memory decline, and core AD biomarkers - in cognitively unimpaired older adults.

Brain, behavior, and immunity·2023
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jun 25, 2025

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

13.7K

从寿命的角度来看,大脑衰老.

Anders Martin Fjell1

  • 1Department of Psychology, Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway. andersmf@psykologi.uio.no.

Current topics in behavioral neurosciences
|May 26, 2024
PubMed
概括

老化的大脑在不同区域显示出各种变化,影响记忆和执行功能. 区分正常衰老和阿尔茨海默氏症等神经退行性疾病需要一个维度方法和进一步的纵向研究.

科学领域:

  • 神经科学是一个神经科学.
  • 老年学是一门学科.
  • 认知科学 认知科学

背景情况:

  • 大脑在一生中表现出连续的,特定区域的变化.
  • 衰老轨迹在不同大脑区域,特别是时和前额皮层中存在显著差异.
  • 这些大脑变化与情节性记忆和执行功能等认知能力的改变有关.

研究的目的:

  • 审查当前对与年龄相关的大脑变化及其认知相关性的理解.
  • 突出正常衰老和神经退行变化之间的重叠,强调需要一个维度视角.
  • 确定当前研究的局限性,并提出未来的研究方向.

主要方法:

  • 在过去二十年中,对大脑衰老的现有研究进行了审查.
  • 对与认知表现相关的大脑结构/功能变化的研究进行分析.
  • 讨论神经成像研究方法及其局限性.

主要成果:

  • 与年龄相关的显著变化发生在特定的大脑区域,特别是皮和前额皮层.
  • 这些结构性和功能性大脑变化与情节性记忆和执行功能的下降有着适度的联系.
  • 正常衰老和早期神经退行过程 (例如,阿尔茨海默病) 的区别往往是模糊的,需要一个维度视图.
关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.大脑衰老的老化在海马体内,海马体磁共振成像技术 磁共振成像

更多相关视频

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.3K
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.0K

相关实验视频

Last Updated: Jun 25, 2025

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

13.7K
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.3K
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.0K

结论:

  • 维度方法对于理解衰老中的认知衰退至关重要,超越严格的正常性/病理性二分法.
  • 通过综合认知测试和脑成像进行进一步的纵向研究是必不可少的.
  • 解决选择偏见和提高老化神经成像研究的代表性对于未来的进步至关重要.