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Updated: Jul 10, 2026

Solid Lipid Nanoparticles SLNs for Intracellular Targeting Applications
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固体脂质纳米颗粒:对其生物医学应用和制备的审查

Mayukh Jana1, Ujjwal Kumar Biswas2, Chandra Sekhar Patro1

  • 1School of Pharmacy, Centurion University of Technology and Management, Centurion University, Bhubaneswar, Odisha, India.

Pharmaceutical nanotechnology
|May 27, 2024
PubMed
概括

固体脂质纳米颗粒 (SLN) 是多功能纳米载体,可以改善药物输送. 本综述详细介绍了SLN制备方法,物理化学特性和生物医学应用.

关键词:
固体脂质纳米粒子 固体脂质纳米粒子生物医学应用.物理化学行为.准备技术 准备技术

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After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...