骨髓细胞NCOA4隔离器KEAP1以减少铁死,以保护小鼠免受沙门氏菌感染

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Updated: Jun 25, 2025

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Mariella Arcos1, Zhaoli Liu1, Luke B Villareal1

  • 1Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131.

Research square
|May 27, 2024
PubMed
概括

核受体共激活剂4 (NCOA4) 缺乏在骨髓细胞恶化沙门氏菌感染,增加铁和氧化应激. 恢复NCOA4或激活NRF2可以防止沙门氏菌引起的结肠炎.

关键词:
沙门氏菌是一种沙门氏菌.铁的代谢 铁的代谢巨细胞是什么?巨细胞是什么?氧化应激是一种氧化应激.

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