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稳定,慢性体外录制来自一个完全无线的潜体内65,536电极脑电脑接口设备.

Taesung Jung1, Nanyu Zeng1, Jason D Fabbri1

  • 1Department of Electrical Engineering, Columbia University; New York, NY 10027, USA.

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概括

研究人员开发了一种灵活的,高密度的微电皮质图 (μECoG) 脑电脑接口 (BCI) 用于高级神经记录. 这种微创设备为未来人类应用提供了高带宽,可靠的大脑信号解码.

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科学领域:

  • 神经科学是一个神经科学.
  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学

背景情况:

  • 大脑-计算机接口 (BCI) 对人类应用至关重要.
  • 现有的BCI技术在体积效率和侵入性方面存在局限性.
  • 下一代BCI需要在小型化和整合方面取得进展.

研究的目的:

  • 开发一种具有较小侵入性,高带宽的BCI,并提高体积效率.
  • 创建一个灵活的微电皮质谱 (μECoG) 装置,具有高密度的记录通道.
  • 在动物模型中证明慢性,可靠的神经记录和信号解码.

主要方法:

  • 在CMOS基板上制造50μm厚的灵活的μECoG BCI.
  • 集成256x256电极阵列 (65,536通道) 与信号处理,遥测和无线供电.
  • 在猪和非人类灵长类动物的硬膜下部植入,用于慢性记录.
  • 与外部中继站进行双向无线通信.

主要成果:

  • 与其他BCI技术相比,在体积效率方面取得了数量级的改进.
  • 在猪群中长达2周,在非人类灵长类动物中长达2个月的可靠记录.
  • 在高时空分辨率下成功解码了来自体感官,运动和视觉皮层的大脑信号.

结论:

  • 开发的μECoG BCI代表了神经接口技术的重大进步.
  • 该设备可实现最小侵入性,高带宽的大脑信号采集和解码.
  • 这项技术有可能彻底改变需要先进的大脑与计算机交互的人类应用程序.