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Updated: Jun 25, 2025

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
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使用αDdCBEs进行无限制精确的线粒体基因组编辑

Santiago R Castillo, Brandon W Simone, Karl J Clark

    bioRxiv : the preprint server for biology
    |May 27, 2024
    PubMed
    概括

    研究人员开发了新的基编辑器 (αDdCBEs),可以克服编辑线粒体DNA (mtDNA) 的局限性. 这些先进的编辑器允许在以前无法访问的mtDNA站点进行精确的C•G-to-T•A转换,从而提高治疗潜力.

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