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Updated: Jun 25, 2025

CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis
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CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis

Published on: April 25, 2022

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低拷贝的CRISPR-Cas13d可以缓解附带RNA裂变

Sydney K Hart, Hans-Hermann Wessels, Alejandro Méndez-Mancilla

    bioRxiv : the preprint server for biology
    |May 27, 2024
    PubMed
    概括

    CRISPR-Cas13d RNA的向精确,但高表达可能会导致不需要的附带RNA降解. 研究人员发现,低表达降低了这种风险,使得有效的转录组扰乱.

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    CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.07:46

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