基于氧的自调节指数与aSAH中的临床结果和扩散脱极化相关
medRxiv : the preprint server for health sciences
|May 27, 2024
概括
动脉瘤下arachnoid出血 (aSAH) 中大脑自调节受损与更糟糕的结果和扩散脱极化 (SD) 事件有关. 监测大脑氧化 (ORx,OSRx) 对于这些患者的血压管理至关重要.
科学领域:
- 神经科学是一个神经科学.
- 临界护理医学 临界护理医学
- 神经学 神经学
背景情况:
- 大脑自调节障碍是动脉瘤下关节出血 (aSAH) 的潜在治疗点.
- 自身调节受损与扩散脱极化 (SD) 事件之间的关系需要进一步研究.
- 评估自我监管的持续措施各不相同,需要标准化的方法.
结论:
- 大脑自调节受损,特别是当ORx和OSRx评估时,与aSAH中不良的临床结果和SD的发展有关.
- 建议使用ORx和OSRx监测自身调节,以指导aSAH患者的最佳平均动脉压管理.
- 这些发现表明ORx和OSRx在aSAH中优化大脑 perfusion 压力方面比内压力更具信息性.
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