一种新的方法来预防,诊断和治疗非洲的乙型肝炎
C Wendy Spearman1, Monique I Andersson2,3,4, Bisi Bright5,6
1Division of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
BMC global and public health
|May 27, 2024
概括
乙型肝炎影响了非洲8200万人,导致严重的肝病和死亡. 简化治疗和社区计划对于打击低诊断和治疗率至关重要,旨在消除乙型肝炎.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 乙型肝炎病毒 (HBV) 感染是世卫组织非洲地区肝病的主要原因,有8200万人受到影响.
- 尽管有疫苗和治疗方法,但每年新感染率高,诊断/治疗率低,导致每年8万人死亡.
- 护理障碍包括复杂的指导方针,缺乏诊断,资金不足和有限的医疗保健基础设施.
研究的目的:
- 为了强调非洲的乙型肝炎的严重负担.
- 确定有效预防和治疗乙型肝炎的障碍.
- 为更广泛的可访问性提出简化和扩展的治疗策略.
主要方法:
- 在世卫组织非洲地区对当前乙型肝炎流行病的分析.
- 审查现有的预防和治疗挑战.
- 倡导以简化标准进行分散的,以社区为基础的治疗计划.
主要成果:
- 只有不到2%的乙型肝炎患者被诊断出来,只有0.1%接受治疗.
- 延迟诊断往往导致晚期肝病,包括肝硬化和肝细胞癌 (HCC).
- 当前的治疗指南可能无法充分识别所有处于风险的患者.
结论:
- 迫切需要简化,扩大乙型肝炎治疗标准,以及为低资源环境提供分散的护理模式.
- 将乙型肝炎护理纳入现有卫生计划和增加资金是必不可少的.
- 加快消除乙型肝炎需要政策变化,行业合作和研究.
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