艾滋病毒感染者中TPT启动和完成的特征
1U.S. Centers for Disease Control and Prevention (CDC), Lilongwe, Malawi.
IJTLD open
|May 27, 2024
概括
结核病预防治疗 (TPT) 的接受率和完成率在马拉维艾滋病毒感染者 (PLHIV) 中仍然很低. 提高需求和坚持是改善这一群体中TPT结果的关键.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 艾滋病毒/艾滋病研究研究
背景情况:
- 结核病预防治疗 (TPT) 对于减少艾滋病毒感染者 (PLHIV) 患病和死亡至关重要.
- 马拉维已经扩大了TPT的规模,但监测和评估过程需要改进.
- 本研究使用国家调查数据评估了TPT的采用和完成.
研究的目的:
- 估计马拉维的自我报告的艾滋病毒阳性个体中TPT吸收和完成率.
- 为了确定与这一群体中TPT吸收相关的因素.
主要方法:
- 马拉维基于人口的HIV影响评估 (MPHIA) 2020-2021年调查数据的分析.
- 估计TPT的流行率和完成比例.
- 双变量和多变量后勤回归以确定与TPT吸收相关的因素.
主要成果:
- 38.8%的HIV阳性受访者表示曾经服用过TPT.
- 与北方相比,中部 (8.0x) 和南部 (5.2x) 地区的TPT吸收率明显高.
- 在最高财富五分位数 (1.9倍) 和接受抗逆转录病毒治疗超过10年的患者 (2.1倍) 中,观察到TPT吸收的几率更高.
- 只有56.2%的目前TPT患者完成了超过6个月的治疗.
结论:
- 在马拉维的自我报告的艾滋病毒阳性个体中,TPT的吸收和超过6个月的治疗持续时间的完成是不理想的.
- 建议采取有针对性的干预措施,以提高需求和改善治疗坚持.
- 加强监测和评估系统对于有效的TPT计划至关重要.
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