疫苗接种及其对COVID-19患者肺部参与的影响:印度的一项回顾性研究
Suhasini Balasubramaniam1, Priyadarsini Bose2, Pravin Kumar Raviganesh3
1Radiodiagnosis, Government Stanley Medical College and Hospital, Chennai, IND.
Cureus
|May 27, 2024
概括
接种COVID-19疫苗,包括CoviShield®和Covaxin®,可以显著减少患者的肺部参与. 这一发现支持对疫苗的信任和接种,以减轻大流行.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 免疫学 免疫学 免疫学
背景情况:
- 由于COVID-19大流行,印度需要快速开发疫苗,印度生产CoviShield®和Covaxin®.
- 疫苗犹对广泛的COVID-19免疫接种工作构成了挑战.
- 了解疫苗对疾病严重程度的有效性对于公共卫生战略至关重要.
研究的目的:
- 评估COVID-19疫苗接种情况与感染患者肺部感染程度之间的关系.
- 提供证据来打击疫苗犹,并促进印度的疫苗接受.
主要方法:
- 印度奈的272名COVID-19患者的回顾性横截面研究 (2021年5月至7月).
- 被归类为接种疫苗 (CoviShield®或Covaxin®) 或未接种疫苗的患者.
- 通过CT胸部扫描评估的肺部感染;统计分析对不同组的严重程度进行了比较.
主要成果:
- 与未接种疫苗的患者 (34.8%) 相比,接种疫苗的患者的平均肺部参与率 (28%) 显着较低.
- 在CoviShield®和Covaxin®接受者之间没有发现肺部参与的显著差异.
- 结果表明,疫苗接种对重症肺病具有普遍的保护作用.
结论:
- 接种COVID-19疫苗有效地减少了患者肺部感染的严重程度.
- 保护性益处在不同类型和剂量的疫苗中是一致的.
- 研究结果强调了疫苗接种在管理COVID-19影响和支持持续免疫计划中的关键作用.
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