相关实验视频

Updated: Jun 25, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing

Published on: July 5, 2019

同时使用L248V与E225V在BCR-ABL基因中的突变,与快速慢性髓性白血病,淋巴细胞突发病危机相关

Songphol Tungjitviboonkun¹, Pawitthorn Wachirapornpruet¹, Sorrawit Unsuwan²

¹Department of Medicine, Sirindhorn Hospital, Bangkok, THA.

|May 27, 2024

概括

本案例研究突出了一个罕见的慢性髓性白血病 (CML) 病例,由于独特的BCR-ABL1突变,该病例进展为淋巴细胞爆发危机. 了解这些突变对于有效的CML治疗策略至关重要.

科学领域:

血液学血液学血液学
在瘤学瘤学.
分子生物学分子生物学

背景情况:

慢性髓性白血病 (CML) 是由费城染色体定义的一种骨髓增殖性瘤.
铁氨酸激酶抑制剂,如伊马替尼,显著改善了CML治疗结果.
然而,疾病进展和抵抗机制仍然是一个临床挑战.

关键词:

所有的一切,所有的一切.这是一种BCR-ABL突变.爆发危机爆发危机慢性骨髓性白血病慢性骨髓性白血病这里是cml cml.伊马替尼布 (Imatinib) 的使用情况

更多相关视频

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

Associated Chromosome Trap for Identifying Long-range DNA Interactions

Associated Chromosome Trap for Identifying Long-range DNA Interactions

Published on: April 23, 2011

相关概念视频

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...