双边COVID-19肺炎患者的肺扩散能力:一个为期三个月的随访研究
Marina Vasilj1, Kristina Galic1, Tanja Zovko1
1Department of Lung Diseases, University Clinical Hospital Mostar, Mostar, BIH.
Cureus
|May 27, 2024
概括
这项研究调查了COVID-19肺炎后的短期肺功能恢复. 肺扩散和螺旋计参数在感染后三个月内显著改善.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 可能导致严重的肺炎,并可能导致长期的呼吸系统后果.
- 评估COVID-19后的肺扩散和肺功能对于了解恢复轨迹至关重要.
研究的目的:
- 评估COVID-19感染对肺扩散和肺功能的短期 (三个月) 影响.
- 为了确定中度至重度COVID-19肺炎患者的康复程度.
主要方法:
- 81名RT-PCR患者的前性研究证实了COVID-19肺炎.
- 肺功能测试,包括肺部对一氧化碳的扩散能力 (DLCO) 和螺旋计,在感染后的1个月和3个月进行.
- 使用了MasterScreen Body Jaeger和MasterScreen PFT Jaeger设备,遵循美国胸腔协会的指南.
主要成果:
- 感染后三个月观察到强迫生命能力 (FVC),FEV1,FEV1/FVC比率和肺总容量 (TLC) 的显著增加.
- 扩散能力参数,DLCO/VA,在三个月后显示完全恢复.
- 即使在三个月后,DLCO/SB仍然低于正常值,这表明肺扩散的某些方面持续受损.
结论:
- 肺功能,包括螺旋测量和DLCO/VA,在COVID-19感染后一到三个月表现出显著的恢复.
- 虽然整体肺功能大大改善,但DLCO/SB表明,一些扩散异常可能会持续超过三个月.
- 调查结果强调,在COVID-19感染后的一个月内部分恢复,并在三个月内显著恢复.
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