环开聚合乳液模板深系统单体的环开聚合,用于控制可降解性的宏性聚合物
Martín Castillo-Santillan1,2, Priscila Quiñonez-Angulo1, Dina Maniar2
1Centro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México Querétaro QRO 76230 Mexico jmota@fata.unam.mx.
概括
这项研究开发了新的可生物降解聚合物,使用无溶剂方法用于组织工程和分离应用. 由此产生的宏性材料显示出作为石油水分离的可降解吸附剂的前景.
科学领域:
- 聚合物化学 聚合物化学
- 材料科学 材料科学 材料科学
- 生物材料是一种生物材料.
背景情况:
- 生物降解的聚烯,如聚烯-乳酸 (PLLA) 和聚烯-烯酸 (PCL),对于组织工程和分离至关重要.
- 为定制的聚合物架构开发高效的合成方法至关重要.
研究的目的:
- 合成具有相互连接的宏性功能生物降解聚合物.
- 设计可聚合的高内部相乳液 (HIPEs),用于创建宏的结构.
- 评估合成的多HIPEs的降解和吸附特性.
主要方法:
- 使用功能性宏基启动剂 (多聚烯三醇 (PCLT) 和聚乙烯糖醇 (PEG)) 的液体深系统单体 (DESm) 的无溶剂环开聚合 (ROP).
- 使用DESm和宏观发起者设计和配制可聚合的HIPE.
- 在HIPE乳液内有机催化ROP.
- 聚合物复制品的特性,包括多孔性,降解和油吸附能力.
主要成果:
- 分支或线性PLLA共聚合物根据使用的宏观启动器而形成.
- 稳定的HIPEs在37°C时被有效地配制和聚合.
- 由此产生的多HIPE表现出相互连接的巨孔结构,并在PBS中保持机械稳定超过30天.
- 聚HIPE证明了有效的原油吸附率为2gg-1.1.
结论:
- 该研究成功合成了具有相互连接的巨性生物降解性PLLA/PCL共聚物和多HIPEs.
- 开发的多HIPE显示出作为可降解的聚合物吸附剂的潜力,用于高效的疏水性流体分离.
- 无溶剂ROP方法和HIPE模板为创建先进生物材料提供了一个多功能平台.
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