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Updated: Jun 25, 2025

High Precision FRET at Single-molecule Level for Biomolecule Structure Determination
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确定FRET辅助蛋白质结构建模的最小距离限制组

Zhuoyi Liu1,2, Alex T Grigas2,3, Jacob Sumner2,3

  • 1Department of Mechanical Engineering and Materials Science, Yale University, New Haven, Connecticut, 06520, USA.

ArXiv
|May 27, 2024
PubMed
概括

需要一些福斯特共振能量转移 (FRET) 约束来准确地模拟细胞环境中的蛋白质动力学,使用分子动力学 (MD) 模拟. 这种方法使得在生物体内能够对蛋白质进行原子级结构建模.

关键词:
在FRET实验中,FRET实验细胞拥挤是因为细胞拥挤.在活体中蛋白质结构分子动力学模拟,分子动力学模拟

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