营养,胃肠道微生物和代谢物在乳腺炎发生和控制中的代谢物
Yue Wang1,2, Yiguang Zhao1, Xiangfang Tang1
1State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
|May 27, 2024
概括
营养和肠道微生物组 (GM) 显著影响牛乳腺炎. 优化饮食和肠道健康提供了非抗生素策略,以预防和管理这种昂贵的乳牛疾病.
科学领域:
- 兽医科学 兽医科学 兽医科学
- 动物营养动物营养
- 微生物学 微生物学
背景情况:
- 牛乳炎是一种流行乳制品行业的疾病,造成了严重的经济和动物健康损失.
- 虽然病原体入侵是已知的原因,但营养和胃肠道微生物群 (GM) 越来越被认为是乳腺炎症的关键因素.
- 低于最佳的营养,特别是负能量平衡和转基因失调是乳腺炎易感性的危险因素.
研究的目的:
- 审查营养 (能量和微量营养素) 与牛乳腺炎之间的复杂关系.
- 概述胃肠道微生物组及其代谢物在调节乳腺炎症反应中的作用.
- 确定用于预防和缓解乳腺炎的非抗生素策略.
主要方法:
- 文献综述侧重于研究营养,胃肠道微生物组和牛乳腺炎的研究.
- 对链接饮食成分,转基因成分,代谢物和乳腺健康数据的分析.
- 对非抗生素干预措施的证据综合.
主要成果:
- 低于最佳的营养,特别是负能量平衡,增加了奶牛乳腺炎的易感性.
- 胃肠道微生物组失调,以减少多样性和增加病原体为特征,通过肠-乳腺通路导致乳腺炎.
- 来自抗生素转基因的亲炎性代谢物可以直接影响乳腺炎症.
结论:
- 营养和胃肠道微生物组是牛乳腺炎的关键决定因素.
- 饮食干预,包括微量营养素和纤维,以及微生物组调节 (益生菌,SCFA),提供了有希望的非抗生素策略.
- 针对营养和肠道健康是有效的乳腺炎管理的关键.
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