具有不同pH值的氧离子溶液对视体中突变型链球菌的有效性
Xu Ming1, Rozita Hassan1, Suharni Mohamad2
1Orthodontic Unit, School of Dental Sciences, Universiti Sains Malaysia, Kelantan, MYS.
Cureus
|May 27, 2024
概括
氧离子溶液显示出对口腔细菌有前途的抗菌作用,在pH 5下具有最佳性能,为口腔健康提供了赫西丁 (CHX) 的潜在替代品. 对于临床应用,需要进一步的研究.
科学领域:
- 口腔微生物学 口腔微生物学
- 抗菌剂 抗菌剂 抗菌剂
- 牙科治疗学 牙科治疗学
背景情况:
- 赫西丁 (CHX) 是一种用于口腔健康的标准抗微生物药物,可以抑制空性细菌和斑块.
- 氧离子溶液作为CHX的替代品的有效性需要研究.
- 了解pH依赖的抗微生物活性对于开发新的口腔护理剂至关重要.
研究的目的:
- 为了比较不同pH值的氧离子溶液的抗菌作用与CHX和化物.
- 评估pH值对氧离子溶液疗效的影响.
- 为了确定氧离子溶液抗菌活性的最佳条件.
主要方法:
- 使用光盘扩散测试来测量抑制区直径.
- 稀释试验确定了最小抑制度 (MIC) 和最小杀菌度 (MBC).
- 对氧离子溶液的不同pH值进行了评估.
主要成果:
- 氧离子溶液证明了pH取决于抗微生物的有效性.
- 在pH 5的氧离子溶液表现出与CHX相比的抗菌性能.
- 轻度酸性条件 (pH5) 一般增强氧离子溶液的抗菌活性,如MIC和MBC值所示.
结论:
- 氧离子溶液,特别是在pH 5时,为CHX提供了可行的替代品,用于对抗空性细菌.
- 氧离子溶液的抗菌疗效受到pH的显著影响.
- 需要对氧离子溶液在口腔健康方面的长期临床应用进行进一步的研究.
相关概念视频
Polyprotic Acids
29.1K
Acids are classified by the number of protons per molecule that they can give up in a reaction. Acids such as HCl, HNO3, and HCN that contain one ionizable hydrogen atom in each molecule are called monoprotic acids. Their reactions with water are:
29.1K
Composition of Polyprotic Acid Solutions as a Function of pH
519
Polyprotic acids of the type H2M constitute two ionizable protons. As a result, on titration with a base, they exhibit two equivalence points in the titration curve. During titration, the species H2M, HM−, and M2− will be present in the solution at different points. The fractions of H2M, HM−, and M2− present at the various instances of the titration are denoted by α0, α1, and α2, respectively.
A graph with the alpha values is plotted against the volume of...
A graph with the alpha values is plotted against the volume of...
519
Weak Acid Solutions
37.9K
Few compounds act as strong acids. A far greater number of compounds behave as weak acids and only partially react with water, leaving a large majority of dissolved molecules in their original form and generating a relatively small amount of hydronium ions. Weak acids are commonly encountered in nature, being the substances partly responsible for the tangy taste of citrus fruits, the stinging sensation of insect bites, and the unpleasant smells associated with body odor. A familiar example of a...
37.9K
Strong Acid and Base Solutions
31.7K
A strong acid is a compound that dissociates completely in an aqueous solution and produces a concentration of hydronium ions equal to the initial concentration of acid. For example, 0.20 M hydrobromic acid will dissociate completely in water and produces 0.20 M of hydronium ions and 0.20 M of bromide ions.
31.7K
Mixtures of Acids
679
The pH of a solution containing an acid can be determined using its acid dissociation constant and initial concentration. If a solution contains two different acids, then its pH can be determined using one of several methods depending on the relative strength of the acids and their dissociation constants.
In a strong and weak acid mixture, the strong acid dissociates completely and becomes a source of almost all the hydronium ions present in the solution. In contrast, the weak acid shows...
In a strong and weak acid mixture, the strong acid dissociates completely and becomes a source of almost all the hydronium ions present in the solution. In contrast, the weak acid shows...
679
Titration of a Strong Acid with a Strong Base
5.4K
During the titration of a strong acid with a strong base, pH calculations are primarily based on the concentration of residual hydronium or hydroxide ions. Initially, a strong acid like hydrochloric acid fully dissociates, creating hydronium and chloride ions, resulting in a low pH. The addition of a strong base like sodium hydroxide alters the concentration of hydronium ions by neutralizing them. As more base is added, the pH gradually increases. At the equivalence point, all hydronium ions...
5.4K


