不间断的坐着对绝经前和绝经后妇女中中心和外周心血管功能的影响
Arsalan Moinuddin1, Keeron Stone2,3, Louise Turner4
1School of Natural, Social and Sport Sciences, University of Gloucestershire, Gloucester, UK. amoinuddin1@glos.ac.uk.
European journal of applied physiology
|May 27, 2024
概括
长时间坐着会影响心血管健康. 这项研究发现,在绝经前和绝经后的妇女之间,坐着2小时的心血管反应没有差异,尽管绝经后的妇女在基线上有更高的动脉硬性.
科学领域:
- 心血管生理学心血管生理学
- 绝经研究 绝经研究
- 运动科学 运动科学
背景情况:
- 长时间不间断地坐着和更年期独立地增加心血管风险.
- 坐着和更年期对心血管功能的综合影响尚不清楚.
研究的目的:
- 为了调查长时间的坐着是否会加剧心血管功能障碍,在绝经后的妇女比在绝经前的妇女更多.
- 为了比较中枢和外围心血管反应,在绝经前和绝经后的妇女之间,不间断地坐着2小时.
主要方法:
- 23名健康女性 (13名绝经前,10名绝经后) 进行了2小时不间断的坐姿.
- 在坐前和坐后测量了带关节脉冲波速率 (cf-PWV),脉冲波分析 (PWA),下肢静脉聚合 (HHb) 和小腿周长.
- 一般线性混合模型和双向重复测量ANOVA用于分析,年龄作为共变量.
主要成果:
- 对于任何结果,绝经状态和坐着时间之间没有发现显著的相互作用.
- 绝经后妇女的基线cf-PWV较高,表明动脉硬度较大.
- 这两组随着时间的推移显示HHb和小腿周长的增加,两组之间的反应没有差异.
结论:
- 虽然绝经后的女性表现出更大的基线动脉硬度,但与绝经前的女性相比,2小时的坐着时间不会对中心或外围心血管反应产生差异性影响.
- 这些发现表明,长时间坐着的负面心血管影响在健康妇女的更年期阶段是相似的.
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