评估社会隔离和孤独的变化与事件心血管事件和死亡率
Yilin Chen1,2, Huachen Xue1,3, Yu Nie1,3
1Center for Sleep and Circadian Medicine, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Road, 510370, Guangzhou, Guangdong, China.
Journal of epidemiology and global health
|May 27, 2024
概括
持续的社会孤立和孤独显著增加了心血管疾病 (CVD) 和死亡率的风险. 这些模式也与心脏功能随着时间的推移而变差有关.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 社会流行病学 社会流行病学
背景情况:
- 改变社会隔离和孤独对心血管疾病 (CVD) 发病率和死亡率的纵向影响尚不清楚.
- 了解这些关联对于公共卫生干预至关重要.
研究的目的:
- 调查社会隔离和孤独的变化模式与发生心血管疾病的风险之间的纵向关联.
- 检查与全因死亡率,心血管疾病死亡率和心脏功能之间的关系.
主要方法:
- 对18258名英国生物库参与者 (38-73岁) 的前性队列研究.
- 社会孤立/孤独被分为四种模式:从来没有,短暂的,偶然的,持久的.
- 通过链接数据确定心血管疾病,死亡率;在子样本中通过MRI评估心脏功能.
主要成果:
- 持续的社会孤立与发生心血管疾病 (HR 1.17) 的更高风险,全因死亡率 (HR 1.42) 和心血管疾病死亡率 (HR 1.53) 相关.
- 持续的孤独表现出类似的关联:发生心血管疾病的风险增加 (HR 1.13),全因死亡率 (HR 1.28) 和心血管疾病死亡率 (HR 1.52).
- 持续的社会隔离和孤独与心脏功能下降相关.
结论:
- 持续的社会隔离和孤独会显著增加发生心血管疾病,死亡率和心脏功能障碍的风险.
- 这些发现强调了持续的社会联系在心血管健康中的关键作用.
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