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0岁至36个月之间的成长模式在美国患有耳鼻裂的儿童中:一项回顾性队列研究
Christy M McKinney1, Waylon Howard2, Kiley Bijlani2
1Seattle Children's Research Institute, Seattle, Washington; Seattle Children's Hospital, Seattle, Washington; University of Washington, Seattle, Washington.
Journal of the Academy of Nutrition and Dietetics
|May 27, 2024
概括
患有 orofacial 裂的儿童经历了增长放缓,特别是在最初的几个月. 追赶增长发生了,但整体增长仍然低于标准,特定的裂类型和并发症影响了结果.
科学领域:
- 儿科生长与发展 儿科生长与发展
- 头骨面部异常 头骨面部异常
- 公共卫生 公共卫生
背景情况:
- 幼儿的长度生长模式与 orofacial 裂并没有很好地理解.
- 面腔裂会影响养,营养和整体发育.
研究的目的:
- 描述从出生到36个月的美国儿童的长度生长模式.
- 确定影响该人口增长轨迹的因素.
主要方法:
- 对1334名患有裂唇,裂唇和 palatus,或裂 palatus 的儿童进行了回顾性队列研究.
- 使用通用线性混合模型分析体重对年龄z分数 (WAZ) 和长度对年龄z分数 (LAZ).
- 将36个月以下的儿童纳入第三级护理儿童医院.
主要成果:
- 在最初的3-4个月里,婴儿的生长显著放缓,随后,根据裂类型的不同,婴儿的增长速度会慢到12个月或36个月.
- 与世界卫生组织标准相比,任何裂类型的儿童都显示出低于平均水平的生长.
- 增长缺陷在患有口唇裂和 palatal cleft 和 palatal cleft 的儿童中比单独患有口唇裂的儿童更为明显.
- 同病症与较低的WAZ和LAZ有关.
结论:
- 患有口唇裂,口腔裂和并发症的婴儿表现出较高的生长不良率.
- 裂口与其他裂口类型相比,单独的裂口与更好的生长结果有关.
- 个体变异性显著影响生长,裂类型和并发症占这种变异性的很小比例.
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