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用心室辅助设备支持的儿科患者预测中风:一个Pedimacs报告

Awais Ashfaq¹, Angela Lorts¹, David Rosenthal²

¹Division of Cardiovascular Surgery, Department of Surgery, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

The Annals of thoracic surgery

|May 27, 2024

概括

儿科心室辅助器械 (VAD) 患者中风风险有所降低,特别是在对体脉动器械中. 风险因素分析有助于完善管理,以获得更好的VAD治疗结果.

科学领域:

儿童心脏病学儿童心脏病学
机械循环支持机械循环支持
神经学神经学

背景情况:

机械循环支持 (Pedimacs) 数据库的儿科机构间注册提供了对需要心室辅助器件 (VAD) 的儿科患者的见解.
脑卒中是儿科VAD患者的重大并发症,需要确定风险因素和趋势.

研究的目的:

用Pedimacs数据分析接受VADs的儿科患者中风发生率.
确定影响该人口中风风险的关键变量.

主要方法:

利用1219名儿科患者 (年龄<19岁) 的数据进行了多相参数危险建模,在2012年至2022年期间植入了1463个VAD.
分析了不同VAD类型和患者人口统计学中的中风风险因素.

主要成果:

在6个月内,从中风的总体自由度从80.2% (2012-2016) 提高到87.9% (2017-2023).
植入式连续VAD显示出最高的无中风率 (91.1%在6个月).
近年来,早期中风风险显著下降 (危险比,5.01),特别是对体外脉动器件的风险.

结论:

儿科VAD患者的整体中风率有所下降,对体外脉动器件接受者有显著的改善.
风险因素分析为识别高风险患者和优化VAD管理策略提供了关键信息.

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