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Updated: Jun 25, 2025

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IKZF2 降解:在设计基于大脑的 PROTAC 时,是时候考虑它了

Minglei Li1,2

  • 1Chemical Biology Center, School of Pharmaceutical Sciences & Institute of Materia Medical, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China.

Chembiochem : a European journal of chemical biology
|May 27, 2024
PubMed
概括

针对蛋白质分解的仿真体 (PROTACs) 通过降解蛋白质提供了新的疾病治疗方法. 本次审查侧重于IKZF2降解剂,这些降解剂对于开发针对cereblon E3结合酶的新型PROTACs至关重要.

关键词:
在 IKZF2这就是 PROTACs.这就是为什么Cereblon.分子粘合剂分子粘合剂蛋白质降解 蛋白质降解

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