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立体图分析对读出细分和单次射击回声平面成像进行比较,以区分光线和非光线乳腺癌.

Yiqi Hu1, Qilan Hu1, Zhiqiang Liu1

  • 1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.

Scientific reports
|May 27, 2024
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概括

这项研究发现,读出细分的回声平面成像 (rs-EPI) 扩散-曲解成像 (DKI) 度量,特别是MK75th,优于单射回声平面成像 (ss-EPI) 在分辨光线与非光线乳腺癌方面.

关键词:
发光器的光线是可以发光的.磁共振成像技术 磁共振成像技术非光线的非光线.Rs-EPI的使用情况.这就是SS-EPI.

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科学领域:

  • 放射学 放射学是一门学科.
  • 在瘤学瘤学.
  • 医疗成像医学成像

背景情况:

  • 区分光线和非光线乳腺癌亚型对于治疗选择至关重要.
  • 扩散权重成像 (DWI) 和扩散-曲解成像 (DKI) 提供了对组织微观结构的洞察力.
  • 比较不同的DWI采集技术,如单次射击回声平面成像 (ss-EPI) 和读取分段回声平面成像 (rs-EPI),对于优化诊断性能很重要.

研究的目的:

  • 为了比较从ss-EPI和rs-EPI序列中得出的DKI和DWI参数在使用组图分析来区分光线与非光线乳腺癌的有效性.
  • 为了确定哪个成像序列和基因图表度量为乳腺癌亚型的诊断提供了最佳的诊断性能.

主要方法:

  • 160名患有乳腺病变的妇女 (111名光线,49名非光线) 在3.0T扫描仪上接受了ss-EPI和rs-EPI DWI序列.
  • 计算了组图指标,包括平均化 (MK),平均扩散 (MD) 和明显扩散系数 (ADC).
  • 使用统计分析 (t-test,Mann-Whitney U) 和ROC曲线分析来评估诊断性能.

主要成果:

  • 与非光线乳腺癌相比,光线乳腺癌的MKmean,MK50th和MK75th值在两个DWI序列中显著更高 (P<0.05).
  • 在区分乳腺癌亚型方面,rs-EPI序列在ss-EPI序列上表现出优越的诊断性能.
  • 来自rs-EPI的MK75th是最有效的单一指标,AUC为0.891,灵敏度为78.4%,特异性为87.8%.

结论:

  • 来自DKI,特别是MK的基因图表指标,在区分光线与非光线乳腺癌方面表现有前途.
  • 与ss-EPI相比,rs-EPI采集技术在这种差异化方面提供了更好的诊断性能.
  • 来自rs-EPI的MK75th是区分光线和非光线乳腺癌亚型的非常有价值的指标.