在最近的小皮下心脏病发作后,经常发生的脑血管事件
Melanie Haidegger1, Nina Klock1, Markus Kneihsl1,2
1Department of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036, Graz, Austria.
Journal of neurology
|May 27, 2024
概括
最近的小皮下心脏病发作 (RSSI) 表明脑血管复发事件的高风险,主要是由于小血管疾病 (SVD). 核磁共振的关键SVD特征预测了这些未来事件,强调了早期检测和管理的必要性.
科学领域:
- 神经学 神经学
- 神经成像是一种神经成像.
- 血管神经学 血管神经学
背景情况:
- 最近的小皮下心脏病发作 (RSSI) 是小血管疾病 (SVD) 相关的缺陷性中风的特征.
- 在RSSI后,关于复发性脑血管事件及其原因的长期数据有限.
研究的目的:
- 调查RSSI后复发性脑血管事件的长期风险.
- 为了确定与复发性缺血和出血事件相关的临床和基于MRI的SVD特征.
主要方法:
- 对332名连续性缺血性中风患者的回顾性分析,MRI确认RSSI (2008-2013).
- 使用多变量考克斯回归,调整年龄,性别,血管风险因素和MRI参数.
- 评估了基线SVD特征 (严格标准) 和中位数12年随访期间的复发事件之间的关联.
主要成果:
- 共有70名患者 (21.1%) 经历了复发性缺血事件 (54次中风,22次TIA),主要与SVD相关 (68%).
- 26名患者 (7.8%) 患有内出血. 糖尿病,严重的白质超强度和大脑微型出血预测了复发性缺血事件.
- 大脑微型出血也增加了内出血的风险. 一个SVD总结得分表明,复发性缺血和出血事件的风险增加.
结论:
- 患有RSSI的患者面临复发性脑血管事件的显著风险.
- 基线MRI上慢性SVD特征的存在大大增加了这种风险.
- 复发性事件,无论是缺血还是出血,主要归因于潜在的SVD.
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