患有白风的患者的流行病学和治疗模式:现实世界的分析
Yuval Ramot1,2, Vered Rosenberg3, Limei Zhou4
1The Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Advances in therapy
|May 27, 2024
概括
Vitiligo 患者的自身免疫和心理疾病的发病率更高. 许多白风患者接受治疗不足,强调需要更好的管理策略.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- Vitiligo 是一种慢性自身免疫性皮肤脱色性疾病,其进展不可预测.
- 它经常与共患性自身免疫和心理疾病有关.
- 关于白风负担和管理的现实数据仍然有限.
研究的目的:
- 分析以色列白风流行病学.
- 调查与白风相关的并发症.
- 为了评估白风患者的治疗模式.
主要方法:
- 对麦卡比医疗服务数据库的回顾性分析.
- 根据年龄,性别和社会经济地位,使患有白风的患者 (2021) 与普通人口相匹配.
- 报告人口统计,发病率,流行率,并发病症和治疗模式.
主要成果:
- 与对照组相比,白病患者患免疫介导 (29.7%) 和心理 (18.7%) 相关疾病的可能性增加.
- 常见的并发症包括亚托邦性皮炎,牛皮,哈希莫托的甲状腺炎,大发性脱发症,抑郁症和睡眠障碍.
- 只有74.8%的白风患者曾经接受过治疗,到2021年底,83.7%没有接受过治疗;局部皮质类固醇和氨酸抑制剂是最常见的.
结论:
- Vitiligo 患者表现出更高的免疫相关和心理伴随性疾病的流行率.
- 相当一部分白风患者接受治疗不足或不接受治疗,药物持续性较低.
- 显然需要改善白风的管理策略和更有效的治疗选择.
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