住院患者中患病率和死亡率与hypopituitarism:流行,原因和管理
Fahim Ebrahimi1,2,3, Lukas Andereggen4,5, Emanuel R Christ6
1Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland. fahim.ebrahimi@ki.se.
Reviews in endocrine & metabolic disorders
|May 27, 2024
概括
患有下垂体病的住院患者面临更高的风险,包括更长的住院时间和更高的死亡率. 早期识别和多学科管理对于改善这个脆弱群体的结果至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 内部医学 内部医学
- 关键护理医学 关键护理医学
背景情况:
- 低位症是一种复杂的内分泌疾病,对患者的健康有重大影响.
- 患有下垂体病的住院患者经历了高负担,包括长时间住院和增加ICU入院.
- 与下垂体相关的代谢并发症可能会加剧住院后果.
研究的目的:
- 审查了解住院患者下垂体病的近期进展.
- 概述这一群体的临床影响和管理策略.
- 为在急性住院期间提供优化多学科护理的建议.
主要方法:
- 关于急性护理环境中下垂体病的最新研究的文献综述.
- 对病理生理机制和临床结果的分析.
- 对管理策略的当前证据的综合分析.
主要成果:
- 低垂体病症与停留时间的延长,ICU入院和机械通风有关.
- 这些患者的代谢障碍可能会损害生理功能,恶化结果.
- 有效的管理取决于早期诊断和由多学科团队进行量身定制的激素替代.
结论:
- 住院患有下垂体病的患者有很高的不良事件和死亡风险.
- 优化,多学科的管理对于减轻这些风险至关重要.
- 对具体干预措施的进一步研究可以改善对这一弱势群体的护理.
相关概念视频
Hypoglycemia and Glucagon
256
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
256
Major Hormones and Their Functions
377
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
377
Acute Pancreatitis II: Clinical Manifestations and Management
119
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
119
Adrenal Gland Disorders
1.5K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.5K
Alterations in Blood Pressure
1.2K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
1.2K
Diabetes: Management and Pharmacotherapy
265
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
265


