[皮肤瘤治疗的副作用]
Jessica C Hassel1, Lisa Zimmer2
1Medizinische Fakultät, Hautklinik und Nationales Centrum für Tumorerkrankungen (NCT), NCT Heidelberg, eine Partnerschaft zwischen DKFZ und dem Universitätsklinikum Heidelberg, Universität Heidelberg, Im Neuenheimer Feld 460, 69120, Heidelberg, Deutschland. jessica.hassel@med.uni-heidelberg.de.
Dermatologie (Heidelberg, Germany)
|May 27, 2024
概括
本综述详细介绍了晚期皮肤癌治疗的副作用,如免疫检查点抑制剂 (ICI) 和向疗法. 了解这些不良事件对于有效的患者管理和监测至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 先进的皮肤癌治疗包括免疫检查点抑制剂 (ICI) 和向疗法.
- 这些疗法,如PD(L) 1,CTLA4,BRAF和MEK抑制剂,改善了患者的治疗结果.
- 不同的治疗方式表现出不同的副作用概况.
研究的目的:
- 提供与皮肤瘤治疗相关的副作用的全面概述.
- 根据当前的文献,讨论这些不良事件的管理策略.
主要方法:
- 皮肤瘤疗法及其副作用的文献综述.
- 专注于特定药物的关键不良事件,包括ICI,mogamulizumab,tebentafusp,BRAF/MEK抑制剂和伊马替尼.
主要成果:
- 副作用可以影响所有器官系统.
- 免疫检查点抑制剂 (ICI) 可能导致慢性和长期的不良影响.
- 考虑了mogamulizumab,tebentafusp,BRAF/MEK抑制剂和伊马替尼的特定副作用.
结论:
- 皮肤癌治疗的副作用可以影响任何器官系统.
- 密切监测和患者教育至关重要,特别是对于ICI,因为潜在的慢性伤害.
- 及时识别副作用的发生,包括延迟发生,对于及时诊断和治疗的启动至关重要.
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