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低前切除综合征表型-不同患者的不同症状概况
Sireesha Koneru1,2,3, Julie Cornish4,5, Pierre H Chapuis1,2,3
1Concord Repatriation General Hospital, Concord Institute of Academic Surgery, Sydney, New South Wales, Australia.
结直肠癌手术后肠道功能障碍显著影响患者的满意度和生活质量. 解决疏散和储存症状对于改善前切除 (AR) 后的结果至关重要.
科学领域:
- 结肠直肠癌 (CRC) 生存率研究.
- 胃肠道手术的结果.
- 患者报告的功能结果.
背景情况:
- 功能性结果对结直肠癌 (CRC) 存活率越来越重要.
- 现有的文献可能低估了疏散功能障碍对CRC前切除术后 (AR) 患者满意度的影响.
- 了解AR后肠道功能障碍对于改善患者健康至关重要.
研究的目的:
- 调查后AR储存和疏散功能障碍症状对患者满意度的影响.
- 评估这些症状对健康相关生活质量 (HRQoL) 的影响.
- 突出记录特定肠道功能障碍症状的重要性.
主要方法:
- 在澳大利亚一家医院对248名CRC后AR患者 (2012-2021) 的横截面研究.
- 使用的验证得分:低前切除综合征 (LARS),圣马克斯失禁,克利夫兰诊所便秘和阿尔托马雷阻塞性排泄综合征.
- 评估患者满意度 (利克尔特尺度) 和HRQoL (SF36v2®),使用线性回归来分析症状关联.
主要成果:
- 六种疏散功能障碍症状 (例如,紧张,未成功的尝试,数字化) 和四种存储症状 (例如,浮泄漏,紧急) 负面影响了患者的满意度.
- 很大一部分患者经历了排气功能障碍,即使是那些"没有LARS" (44.5%).
- 储存和疏散功能障碍症状都与患者满意度降低和HRQoL相关.
结论:
- 术后储存和排气功能障碍症状会对AR后的患者满意度和HRQoL产生不利影响.
- 对排气功能障碍症状的全面记录对于患者护理至关重要.
- 需要进一步的研究来开发特定于LARS的患者满意度加权HRQoL仪器.
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