在患有不对称初级角关闭疾病的受试者中,比较眼内压力和前段参数
Shayne S Tan1, Tin A Tun1,2, Tin Aung1,2
1Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Clinical & experimental ophthalmology
|May 28, 2024
概括
与其他眼睛相比,主角闭眼光眼 (PACG) 的眼睛显示出更高的眼内压力 (IOP) 和更窄的前部细分. 这些因素增加了慢性升高的内腔压力和光眼神经病变的风险.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 前段成像前段成像的使用
背景情况:
- 主要角闭眼光眼 (PACG) 是视力丧失的重要原因.
- 了解单方面PACG前部细分差异对于诊断和管理至关重要.
研究的目的:
- 为了比较眼内压力 (IOP) 和前段参数与单侧PACG眼睛之间的眼睛和他们的兄弟眼睛.
- 识别与PACG开发相关的风险因素.
主要方法:
- 360度扫描源光学连贯性断层扫描 (SS-OCT) 用于前部段成像.
- 分析的关键参数包括 iridotrabecular contact (ITC),角度开口距离 (AOD750),虹膜厚度,前腔尺寸和镜头 (LV).
- 此外,还进行了视镜和内脉管测量.
主要成果:
- 与其他眼睛相比,PACG眼睛表现出显著更高的IOP,较小的阴影镜Shaffer等级,以及较大的外围前侧突 (PAS).
- PACG眼睛显示ITC增加,LV更大,AOD750更小,前腔宽度 (ACW),前腔深度 (ACD) 和前腔面积 (ACA).
- 在激光外周 iridotomy (LPI) 之前呈现 IOP 的 1 mmHg 的增加,使得 PACG 的几率增加了 9%.
结论:
- 拥有PACG眼睛的眼睛具有明显的前部细分特征和比其他眼睛更高的IOP.
- 较窄的前腔尺寸和较高的LPI前IOP与慢性升高IOP和玻璃眼光神经病变的风险增加有关.
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