新生儿重症监护室药物管理错误的患病率和相关因素:一个多中心,全国性的直接观察性研究
Josephine Henry Basil1, Chandini Menon Premakumar1, Adliah Mhd Ali1
1Centre for Quality Management of Medicines, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Journal of advanced nursing
|May 28, 2024
概括
在新生儿重症监护室中,药物错误很常见,影响90%以上的新生儿. 关键因素包括静脉注射,缺乏方案和药物复杂性.
科学领域:
- 新生儿重症监护室新生儿重症监护室
- 药物的安全性 药物的安全性
- 临床药房 临床药房 临床药房
背景情况:
- 药物管理错误 (MAE) 对新生儿构成重大风险.
- 了解新生儿重症监护室 (NICU) 中 MAE 的患病率和促成因素对于改善患者的治疗结果至关重要.
研究的目的:
- 为了确定在NICU中新生儿中药物管理错误的流行率.
- 确定与这种脆弱人群中药物管理错误相关的因素.
主要方法:
- 在马来西亚五家公立医院进行了前性直接观察研究.
- 观察了药物制备和使用情况,随后由临床药剂师对图表进行审查和独立识别错误.
- 多变量后勤回归分析确定了与MAE相关的因素.
主要成果:
- 观察到MAE的高率,其中68.0%的剂量含有至少一个错误,影响了92.4%的新生儿.
- 最常见的错误包括错误的注射速率 (21.2%),错误的药物制备 (17.9%) 和错误的剂量 (17.0%).
- 与MAE相关的因素包括静脉注射,缺乏协议,药物数量,护理经验,非通风状态和妊娠年龄.
结论:
- 药物管理错误仍然是NICU中常见的问题.
- 静脉输入路线,缺乏协议,更年轻的妊娠年龄,非通风的新生儿,多药学和护理经验是MAE的重要风险因素.
- 结果可以指导干预措施,以减少新生儿的MAE.
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