SARS-CoV-2对患有下泌尿道症状 (LUTS) 的患者的影响
Marian S Balacescu1,2, Cosmin V Ene1,2, Dragos Eugen Georgescu3,4
1Urology, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU.
Cureus
|May 28, 2024
概括
在患有良性前列腺增生症 (BPH) 的男性中,COVID-19大流行使下泌尿道症状 (LUTS) 恶化. 患有严重COVID-19的患者尿功能和生活质量显著下降,需要医疗干预.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- COVID-19大流行影响了良性前列腺激增症 (BPH) 和下泌尿道症状 (LUTS) 的管理策略.
- 医疗保健提供者重新考虑了BPH治疗,因为它可能对COVID-19的严重程度和进展产生影响.
- 这项研究调查了SARS-CoV-2感染,LUTS恶化和BPH进展之间的关系.
研究的目的:
- 检查SARS-CoV-2感染严重程度与BPH患者LUTS恶化之间的相关性.
- 评估COVID-19对BPH进展和相关尿路症状的影响.
主要方法:
- 在2021年1月至2023年1月期间对138名住院患者 (57-88岁) 进行回顾性分析,这些患者患有SARS-CoV-2和BPH.
- 通过数字直肠检查,PSA水平和超声波确认BPH诊断; COVID-19通过测试确认.
- 外科干预包括通过尿道切除前列腺 (TURP) 和用盐水 (TURPis) 切除前列腺;使用IBM SPSS统计数据进行统计分析.
主要成果:
- 18名患者需要紧急 TURP/TURPis 治疗持续出血,尽管进行了保守的治疗.
- 接受手术的患者住院时间较长 (10.5天而不是7.5天).
- 与COVID前状态相比,在COVID-19感染期间观察到国际前列腺症状评分 (IPSS),排泄后残留物 (PVR) 和生活质量 (QoL) 的显著恶化 (p <0.05).
结论:
- 在BPH患者中,COVID-19感染可能会导致LUTS显著恶化.
- 在急性SARS-CoV-2感染期间,经常推迟慢性BPH的治疗,以减轻风险.
- 严重的COVID-19症状与LUTS进展的较差结果有关.
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