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在患有甲状腺癌的患者甲状腺切除术后尿液外体水平的长期变化:一项前性观察性研究

Chih-Yuan Wang¹, Shyang-Rong Shih¹, Kuen-Yuan Chen²

¹Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

International journal of nanomedicine

|May 28, 2024

概括

甲状腺切除术后尿液外体水平在患有甲状腺癌的患者中没有显著差异. 长期监测这些水平可能有助于评估高风险患者的复发风险.

科学领域:

在瘤学瘤学.
生物化学生物化学
泌尿器科泌尿器科泌尿器科泌尿器科

背景情况:

甲状腺癌复发率可以达到30%.
预测复发风险的有效方法对于患者管理至关重要.
甲状腺切除术后的监测策略需要进一步调查.

研究的目的:

在甲状腺癌患者的甲状腺切除术后,研究尿液外体水平的变化.
为了确定这些水平是否可以作为甲状腺癌复发的预测因素.
为长期跟踪建立基线波动范围.

主要方法:

招募了被诊断为乳头甲状腺癌的成年患者,他们接受了甲状腺切除术.
在入学后12个月收集尿样,一年后再次收集尿样.
利用外体隔离和鉴定技术来比较尿样.

主要成果:

在2年的随访期间,在任何患者身上都没有观察到甲状腺癌复发.
在患者组或时间间隔之间没有发现血清蛋白或尿液外体水平的显著差异.
已知甲状腺癌的高风险因素仅与测量中的水平有轻微的相关性.

结论:

在甲状腺切除术后的甲状腺癌患者中,已确立的血清蛋白和尿液外osomal的长期基底波动范围.
表明在这些既定范围内的度可能表明高风险患者的复发风险较低.
突出了尿液外体对长期复发风险评估的潜在用处.

关键词:

这是一种类.复发性复发性复发性甲状腺球蛋白甲状腺球蛋白甲状腺癌是一种癌症.尿液外基因组是什么

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