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Updated: Jun 25, 2025

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在多发性髓瘤中,EZH2抑制通过ERK1/2信号通路诱导衰老

Shushan Guo1,2,3, Qiongwei Tang2, Xuejie Gao2

  • 1Shanghai Clinical College, Anhui Medical University, Shanghai 200072, China.

Acta biochimica et biophysica Sinica
|May 28, 2024
PubMed
概括

增强质同源2 (EZH2) 抑制剂通过增加Lamin B1和促进ERK1/2酸化,触发了多发性骨髓瘤 (MM) 中的细胞衰老. 这揭示了MM衰老诱导的新机制.

关键词:
在 EZH2 中使用.拉明 B1 的使用.在RRM2中使用RRM2.细胞衰老 细胞衰老多发性骨髓瘤是多发性骨髓瘤的一种疾病.

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