在子中的真菌毒性病的概述
1Department of Clinical Pathology, Idexx Laboratories, Wetherby, West Yorkshire, UK.
概括
本综述详细介绍了子中真菌毒素的临床病理学和本病理学影响. 它为兽医专业人员整合了有关烟素, ochratoxins,亚毒素,trichothecenes和zearalenone的碎片化证据.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 毒理学 毒理学 毒理学
- 动物病理学 动物病理学
背景情况:
- 菌毒症虽然经常与大型动物有关,但越来越多地影响子等伴侣动物.
- 子被用作实验室模型,导致对真菌毒素影响的研究增加.
- 关于子真菌毒性病的现有证据是零碎的,缺乏最近的全面审查.
研究的目的:
- 整理和审查子中关键菌毒素的临床病理学和本病理学影响.
- 为了解这种物种中的真菌毒性病提供一个综合资源.
- 解决有关特定真菌毒素对子健康影响的知识差距.
主要方法:
- 文献综述侧重于实验研究和已发表的证据.
- 对与子中菌毒素暴露相关的临床病理学和组织病理学发现的分析.
- 识别并专注于影响子的最重要的真菌毒素:烟素, ochratoxins,亚毒素,trichothecenes和zearalenone.
主要成果:
- 子中的菌毒症通常是亚临床的,但可以表现为体重减轻,厌食症,胃肠道疾病,生长迟缓,生殖问题和增加感染易感性.
- 诊断包括临床病史,症状,实验室发现,以及在料或组织中确认真菌毒素水平.
- 具体的临床病理学和组织病理学影响因涉及的真菌毒素而异.
结论:
- 本综述综合了目前关于子菌毒素影响的知识,突出了它们多样化的临床病理学和本病理学影响.
- 它是兽医,诊断医生和研究人员处理子菌毒性病的重要资源.
- 进一步的研究可能会从更统一的方法来研究这些复杂的毒理学效应在子中受益.
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