希腊的母亲和新生儿维生素D (25(OH) D水平之间的相关性:一个横截面研究
Artemisia Kokkinari1, Maria Dagla1, Evangelia Antoniou1
1Department of Midwifery, School of Health & Care Sciences, University of West Attica, 12243 Athens, Greece.
Clinics and practice
|May 28, 2024
概括
在希腊,孕产妇维生素D缺乏症 (VDD) 很普遍. 产前维生素D补充剂改善了母亲和新生儿的维生素D水平,但新生儿仍然没有足够的维生素D,表明需要更高剂量.
科学领域:
- 内分泌学 在内分泌学.
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 营养科学 营养科学
背景情况:
- 维生素D缺乏 (VDD) 是一个全球性的健康问题,特别是在怀孕期间.
- 关于希腊出生时母亲和新生儿维生素D (25(OH) D水平之间的相关性数据有限.
- 研究这种关联对于了解地中海人群中VDD至关重要.
研究的目的:
- 调查希腊出生时母体和新生儿25OH) D水平之间的关联.
- 评估低剂量产前维生素D补充剂 (400-800 IU) 对这些水平的影响.
- 为地中海国家提供有关母亲和新生儿VDD的证据.
主要方法:
- 这是一项涉及2019年9月至2022年1月248对母婴的横截面研究.
- 对带血样本进行分娩时25(OH) D度的分析.
- 统计分析包括后勤回归,奇方位测试和皮尔森相关性来评估关联和影响因素.
主要成果:
- 在母亲和出生时的新生儿中观察到高患病率的VDD,特别是在秋季和冬季.
- 低剂量产前维生素D补充剂增加了母亲和新生儿的25(OH) D水平.
- 尽管服用补充剂,新生儿的25(OH) D水平仍然不足,与母亲的水平不同,该水平达到足够水平.
结论:
- 在孕期的孕产妇和新生儿25OH) D水平之间存在强烈的关联.
- 新生儿始终表现出低于他们的母亲的25OH) D度,无论补充剂.
- 在怀孕期间对更高剂量的维生素D补充剂进行进一步的研究是有必要的,以获得最佳的母婴维生素D状态.
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