银化物化合物K在辅助剂诱导的关节炎大鼠中具有抗炎作用,而不会诱导葡萄糖代谢障碍

Lijuan Mao1, Lili Liu1, Jun Li1

  • 1Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine of Education Ministry, Anhui Cooperative Innovation Center for Anti-inflammatory Immune Drugs, Center of Rheumatoid Arthritis of Anhui Medical University, Hefei, 230032, China. wwei@ahmu.edu.cn.

Food & function
|May 28, 2024
PubMed
概括

银化物化合物K (GCK) 提供抗炎功效,而不会引起高血糖症,与传统的葡萄糖皮质激素 (GC) 不同. 这项研究揭示了GCK针对葡萄糖皮质体受体 (GR) 的独特结合部位,避免了不良代谢影响.

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