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Updated: Jun 25, 2025

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry
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小鼠基托赫索基因酶异型C的迈凯利斯样复合体

William C Gasper1, Sarah Gardner2, Adam Ross2

  • 1Program in Biochemistry and Molecular Biology, Boston University, Boston, MA 02215, USA.

Acta crystallographica. Section D, Structural biology
|May 28, 2024
PubMed
概括

果糖代谢和相关疾病中,基酶 (KHK) 是至关重要的. 这项研究呈现了小鼠KHK-C与果糖和ADP结合的高分辨率结构,揭示了对催化和潜在治疗向重要的构造变化.

关键词:
在X射线晶体学.形状的变化 形状的变化果糖酸酶是什么 果糖酸酶是什么 果糖酸酶是什么果糖的新陈代谢过程土壤状态 土地状态诱导适合的诱导适合鼠标基托赫克索基因酶异型C蛋白质结构 蛋白质结构

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