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Updated: Jun 25, 2025

Author Spotlight: Visualizing Single-Stranded DNA During DNA Repair for Therapeutic Insights
08:30

Author Spotlight: Visualizing Single-Stranded DNA During DNA Repair for Therapeutic Insights

Published on: December 22, 2023

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Sch9S6K 控制 DNA 修复和 DNA 损伤反应效率在衰老细胞

Chiara Lucca1, Elisa Ferrari1, Ghadeer Shubassi2

  • 1IFOM ETS - The AIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy.

Cell reports
|May 28, 2024
PubMed
概括

衰老细胞显示DNA修复和DNA损伤反应 (DDR) 的受损. 通过抑制TORC1-Sch9信号传递,通过调节蛋白酸酶2A (PP2A) 活性,恢复DNA修复并增强老细胞中的DDR.

关键词:
在ATR/Mec1中使用.科普:分子生物学 分子生物学在DDR中,DDR是指DDR.修复DNA的修复DNA的修复在PP2A中,PP2A是PP2A.在Rad53中,Rad53是什么?Sch9 Sch9 的意思是什么?在Snf1中,Snf1是Snf1的意思.在TORC1中,紫外线损伤的病变 紫外线损伤衰老的衰老 衰老的衰老

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