在骑自行车时,在膝盖延伸肌肉上引起的跨脑磁刺激反应的可靠性
Jenny Zhang1, Zachary J McClean1, Neda Khaledi1,2
1Faculty of Kinesiology, University of Calgary, KNB 420, 2500 University Drive NW, Calgary, AB, T2N 1N4, Canada.
Experimental brain research
|May 28, 2024
概括
这项研究发现,运动唤起潜力 (MEP) 和长间隔内皮层抑制 (LICI) 在骑自行车时可靠. 短间歇性皮质内抑制 (SICI) 在会议中显示出不良可靠性,但在会议内可靠.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 运动生理学 运动生理学
背景情况:
- 超磁刺激 (TMS) 评估皮质运动刺激性和抑制性.
- 在像骑自行车这样的动态运动中,TMS的应用较少被探索.
- 在疲劳的循环任务中,TMS配对脉冲的可靠性需要评估.
研究的目的:
- 为了评估运动唤起潜力 (MEP) 和皮质内抑制 (SICI,LICI) 在疲劳单腿骑自行车任务中的可靠性.
- 为了评估TMS的测量,大侧肌和大腿直肌肌肌肉.
主要方法:
- 9名健康的成年人进行了两次相同的单腿骑自行车,以达到疲劳.
- 在TMS单脉冲和对脉冲,以及大腿神经刺激 (Mmax) 在基线和循环期间每5分钟进行一次.
- 使用类内相关系数 (ICC) 来确定MEP的可靠性,将其规范化为Mmax (MEP·Mmax-1),SICI和LICI.
主要成果:
- 在会话中,MEP·Mmax-1和LICI显示出极好的可靠性 (ICC>0.9),而SICI则很好 (ICC:0.7-0.9).
- 在基线会议之间,Mmax和MEP·Mmax-1显示出良好的可靠性 (ICC:0.7-0.9),LICI是中度的 (ICC:0.5),SICI是差的 (ICC:0.3).
- 在疲劳循环时,Mmax (ICC>0.8),MEP·Mmax-1和LICI (ICC:0.5-0.9) 显示出良好的可靠性,而SICI的可靠性仍然很差 (ICC:0.3-0.6).
结论:
- 运动唤起的潜能 (MEP·Mmax-1),最大的股骨神经刺激 (Mmax) 和长间隔的皮内抑制 (LICI) 是骑自行车时可靠的测量.
- 短间歇性皮质内抑制 (SICI) 在不同疗程中显示出不良可靠性,但在单个疗程内可靠.
- 模式特定测试测量至关重要,TMS措施如Mmax,MEP·Mmax-1和LICI适用于自行车研究.
相关概念视频
Muscle Contraction
Muscle Contraction
In skeletal muscles, acetylcholine is released by nerve terminals at the motor endplate—the point of synaptic communication between motor neurons and muscle fibers. The binding of acetylcholine to its receptors on the sarcolemma allows entry of sodium ions into the cell and triggers an action potential in the muscle cell. Thus, electrical signals from the brain are transmitted to the muscle. Subsequently, the enzyme acetylcholinesterase breaks down acetylcholine to prevent excessive muscle...
Motor Unit Stimulation
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
Somatic Spinal Reflexes
Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...


