围产期结局和三胎怀孕的增长不一致性基于胆管性:一个回顾性队列研究
Qing Hu1,2, Zhaomin Zeng1,2, Hongyan Liu1,2
1Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, No. 20, 3 Section, South Renmin Road, Chengdu, Sichuan, 610041, China.
BMC pregnancy and childbirth
|May 28, 2024
概括
三 (TC) 妊娠减少新生儿贫血和输血需求,但增加低蛋白质血. 三胞胎的高出生体重异常 (BWD) 增加了贫血和输血风险,同时也增加了TC怀孕的低蛋白质血症,单牙 (MCDA) 或单牙三 (MCTA) 病例.
科学领域:
- 围产儿医学 围产儿医学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 新生儿科学 新生儿科学
背景情况:
- 三胞胎怀孕发生在全球0.093%的怀孕中,自然发病率为8000分之一.
- 新生儿结局和三胞胎出生体重差异 (BWD) 根据胆管状况有很大差异.
研究的目的:
- 在三胞胎中分析新生儿健康状况和出生体重异常 (BWD) 基于胆管性.
- 为了比较双重 (DC),三重 (TC) 和单重 (MC) 三重怀孕中的孕产妇并发症和新生儿结果.
主要方法:
- 从2001年1月1日至2021年12月31日期间,对136例三胎妊娠的回顾性研究.
- 对孕产妇和新生儿结局,三人间BWD,新生儿发病率和死亡率的分析.
- 对DC (41例),TC (37例) 和MC (21例) 组的结果进行比较,不包括胎儿损失的怀孕.
主要成果:
- 子宫内,新生儿和围产期死亡率分别为10.29%,13.07%和24.26%.
- 新生儿低蛋白血症,高白血症和贫血症显示出基于表性和BWD的显著差异.
- 三 (TC) 妊娠减少了新生儿贫血和输血需求 (AOR=0.084,AOR=0.119),而BWD>25%增加了这些风险 (AOR=10.135,AOR=7.127).
结论:
- 出生体重异常 (BWD) 显著不同于胆管性,影响新生儿的结局.
- 三 (TC) 怀孕与新生儿贫血和输血需求的减少有关,但增加了低蛋白质血.
- 高BWD (>25%) 和特定的胆管类型 (TC,MCDA,MCTA) 会增加新生儿贫血,输血需要和低蛋白血的风险.
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