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Updated: Jun 25, 2025

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
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微凝与不动化的葡萄糖转移酶用于酶性葡萄糖合成

Isabel Katja Sommerfeld1,2, Philip Palm3, Kai Philip Hussnaetter3

  • 1Functional and Interactive Polymers, Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 2, Aachen 52074, Germany.

Biomacromolecules
|May 29, 2024
PubMed
概括

这项研究提出了微凝,用于增强酶性甘氨酸合成. 微凝中的固定酶可以实现高效的级联反应,为自动合成铺平道路.

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相关概念视频

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
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