在西门子VE系列扫描仪上用于磁共振光谱的序列构建块
Jabrane Karkouri1, Christopher T Rodgers1
1Wolfson Brain Imaging Center, University of Cambridge, Cambridge, UK.
NMR in biomedicine
|May 29, 2024
概括
一个新的序列构建块 (SBB) 允许将磁共振光谱 (MRS) 嵌入到现有的MRI序列中,而不需要硬件更改. 这一创新促进了功能MRS和实时运动校正等动态研究,简化了先进的MRI研究.
科学领域:
- 磁共振成像是一种磁共振成像技术.
- 频谱学是一种光谱学.
- 医学物理 医学物理
背景情况:
- 磁共振光谱 (MRS) 对于代谢概况至关重要.
- 动态MRS研究需要无集成到现有的MRI序列.
- 目前嵌入MRS的方法可能是复杂的,并且依赖于硬件.
研究的目的:
- 开发一种新的序列构建块 (SBB),用于将MRS嵌入西门子VE平台序列中.
- 为了实现动态MRS应用,包括功能MRS (fMRS),动态闪和运动校正.
- 简化将MRS集成到各种成像和光谱测序中.
主要方法:
- 开发了一个基于软件的SBB,与西门子VE平台兼容.
- 将SBB集成到一个渐变回忆回声序列中.
- 支持非局部化,单个voxel和化学转移成像技术.
- 启用了同核和异核MRS嵌入.
主要成果:
- 顺利地将SBB集成到一个供应商序列中,使用最少的代码 (15行).
- 动态MRS研究,包括fMRS,在幽灵和志愿者身上进行了证明.
- 获得的光谱和图像显示质量影响微不足道,偶尔会增强核过度修复效应 (NOE).
- SBB支持各种MRS技术和核组合 (例如,1H/X核).
结论:
- 开发的SBB显著降低了实施动态MRS研究的障碍.
- 这种方法促进了实时运动校正和B0-shim更新.
- 对于先进的MRS应用,SBB提供了一种多功能且独立于硬件的解决方案.
关键词:
交联光谱,MRS,序列构建块等.相关概念视频
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