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Updated: Jun 25, 2025

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基于多模型分析的急性髓性白血病预后的细胞表面标记物的识别

Jiaqi Tang1,2,3, Lin Luo1,2,3, Bakwatanisa Bosco1,3

  • 1Department of Bioinformatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, Jiangsu 211166, China.

Journal of biomedical research
|May 29, 2024
PubMed
概括

一个新的9细胞表面标记 (CSM) 模型预测了急性髓性白血病 (AML) 的结果. 这种预后工具可以识别高风险的AML患者,这些患者可能会抵抗化疗,并受益于PI3K抑制剂.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.细胞表面标记器细胞表面标记器药物敏感性 药物敏感性多模型分析分析多模型分析预后 预后 预后

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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