饮食与传染病的关联在英国生物银行
Junlan Tu1, Xuehong Cai1, Yifan Wang2
1Department of Epidemiology, National Vaccine Innovation Platform, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
饮食习惯会影响传染病的风险. 高度加工和红肉摄入增加了风险,而鱼类,奶酪,水果和蔬菜的消费降低了风险. 吃鱼的人感染感染的风险较低.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 人们越来越认识到饮食模式在调节免疫反应和易受传染病影响方面的作用.
- 了解食品组消费与感染风险之间的特定关联对于公共卫生干预至关重要.
研究的目的:
- 调查13个食物组 (或四个更广泛的饮食组) 的摄入频率与传染病发病率之间的关系.
- 为了确定与改变传染病风险相关的特定饮食成分和模式.
主要方法:
- 使用多变量逻辑回归分析.
- 分析了来自英国生物库的487,849名参与者的数据,其中75,209人被诊断患有传染病.
- 进行了调解分析,以探索生物因素的作用.
主要成果:
- 加工肉 (OR=1.0964) 和红肉 (OR=1.0895) 的最高摄入量与感染性疾病的更高风险有关.
- 增加鱼类 (OR=0.8221),奶酪 (OR=0.8822),水果 (OR=0.8867) 和蔬菜 (OR=0.9372) 的消费与较低的感染风险有关.
- 吃鱼的人 (OR=0.8391) 和素食者 (OR=0.9154) 与经常吃肉的人相比,风险较低. 糖化血红蛋白,白细胞计数和BMI被确定为调解剂.
结论:
- 食物组摄入的频率是影响传染病风险的重要因素.
- 饮食模式,特别是更多的鱼类,水果,蔬菜和奶酪消费,与感染易感性降低有关.
- 促进富含鱼类和植物性食品的饮食可能是降低传染病负担的可行策略.
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