减肥手术2年后的微量营养状况:潜在的营养评估
Marianne Côté1,2, Laurence Pelletier1,2, Mélanie Nadeau1
1Quebec Heart and Lung Institute - Laval University, Québec, QC, Canada.
Frontiers in nutrition
|May 29, 2024
概括
双胞胎切换 (BPD-DS) 带有双胞胎切换 (BPD-DS) 的双胞胎胰腺转移提供了显著的体重减轻,但存在风险. 在适当的管理下,BPD-DS,Roux-en-Y胃绕道 (RYGB) 和袖子胃切除术 (SG) 显示出类似的长期营养缺乏率.
科学领域:
- 腹部外科 腹部外科
- 营养科学 营养科学
- 代谢健康 代谢健康
背景情况:
- 双胞胎切换 (BPD-DS) 的双胞胎胰腺转移比Roux-en-Y胃绕道 (RYGB) 或袖子胃切除术 (SG) 实现了更大的体重减轻.
- 由于BPD-DS的低吸收性,人们担心长期的营养缺乏,限制了其广泛采用.
研究的目的:
- 为了前性地评估BPD-DS,RYGB和SG之后的2年营养状况.
- 为了比较体重减轻和关键微量营养素水平,在三种减肥手术中.
主要方法:
- 前性,单中心REMISSION试验,涉及215名接受BPD-DS (n=73),RYGB (n=48) 或SG (n=94) 的患者.
- 评估体重减轻,血清微量营养素水平 (维生素A,B12,D,铁,,副荷尔蒙) 和24个月的补充剂.
- 营养补充剂是根据手术类型和个体患者需求量身定制的.
主要成果:
- 基线维生素D缺乏症在所有组中普遍存在 (38.3%-54.8%).
- 在24个月后,BPD-DS患者的铁,和维生素A水平低于SG患者,但关键微量营养素的整体缺乏率在各组中相似.
- 维生素D和铁缺乏率从基线下降到24个月.
- 大多数BPD-DS患者需要维生素A和维生素D补充剂,超过最初的建议.
结论:
- 在适当的医疗和营养管理下,BPD-DS,RYGB和SG导致2年后主要微量营养素缺乏率相似.
- 目前针对BPD-DS患者的维生素A和D补充指南可能需要向上修订.
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