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乙氨症作为COVID-19在末期病患者中死亡率的预后因素
I Gede Yasa Asmara1, I Gusti Ngurah Ommy Agustriadi1, I Made Sujaya1
1Department of Internal Medicine, Faculty of Medicine, University of Mataram - West Nusa Tenggara General Hospital, Mataram, Indonesia.
Caspian journal of internal medicine
|May 29, 2024
概括
乙素衰弱或低乙素细胞计数是COVID-19患者末期病 (ESKD) 患者死亡率的重要预测因素. 这种情况,连同血液透析,独立增加死亡的风险,在这个脆弱的人群.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 血液学 血液学 血液学
背景情况:
- 埃索诺菲尔在COVID-19中起着已知的作用,但它们在COVID-19患者末期病 (ESKD) 中的重要性尚未得到充分研究.
- 这项研究解决了关于eosinopenia作为ESKD的COVID-19患者死亡率标志物的知识差距.
研究的目的:
- 为了研究患有COVID-19诊断的末期脏病 (ESKD) 患者的死亡率,eosinopenia的预测价值.
- 在ESKD患者中确定COVID-19死亡率的独立预后因素.
主要方法:
- 从2020年5月到2021年10月,对115名患有COVID-19的ESKD患者进行了回顾性研究.
- 进行了幸存者和非幸存者组之间的比较分析,随后进行多变量逻辑回归以确定显著的死亡预测因素.
主要成果:
- 在COVID-19 ESKD患者中,死亡率为25.2%.
- 在未幸存者中 (51.4%) 患有欧氨是普遍存在的.
- 在多变量分析中,确定了乙氨症 (低乙氨基酸计数) 和血液透析是该队列中死亡的独立风险因素.
结论:
- 乙氨是COVID-19患者患有ESKD的常见发现,特别是那些没有生存的人.
- 在住院期间入院时患有乙氨和接受血液透析是ESKD患者COVID-19死亡率的重要风险因素.
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